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IL 4 signaling pathway

PAG Title IL 4 signaling pathway
PAG ID WIG000356
Type P
Source Link MSigDB
Publication Reference NA
PAG Description Interleukin 4 (IL-4) is a cytokine that can lead to development of Th2 cells. The 140 kD IL-4 Receptor (CD124) is found on many cell types, even those of non-hematopoietic origen. The receptor is formed from two chains: IL-4R(alpha) and the IL-2R gamma chain (CD132). Primary signaling is through the JAK/Stat6 pathway and MAPKs.
Species Homo sapiens
Quality Metric Scores nCoCo Score: 2,826
Information Content Rich
Other IDs M5415
Base PAG ID WIG000356
Human Phenotyte Annotation
Curator PAGER curation team
Curator Contact PAGER-contact@googlegroups.com
Gene ID Gene symbol Gene name RP_score
Gene A Gene B Source SCORE

Gene A Gene B Mechanism Source
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